You have a number of options to choose from. First off, do you want to continue working out of the home or be stay home with your children? If you would like to or want to stay home with your small children there are a number of ways to stay home and make money.
First off (if you like beauty, which I see as one of the listed topics above) have you ever considered selling Mary Kay from home? http://www.marykay.com/sellmarykay/default.aspx
If you do, I am friends with someone who does exactly this and I am sure she will help you out. If you do choose this route, please email me and we can talk, perhaps via our personal emails.
I totally understand that you need immediate cash flow, but finding a job is most of the time not immediate. So before you get hired at your next job you can being doing things on the side/part time to make money. Sell things on the internet. (Trust me I know this is not big money but it's something). I sell books, CDs and DVDs on amazon and I have made some good side money for my husband and I. There is a website called etsy.com where people sell all sorts of things they make by hand, http://www.etsy.com/
And of course there is always Ebay. I know people, who have made a good amount of money selling on Ebay, you just have to sell in volume as opposed to something here and there.
I see you have computers as one of your listed topics. As I am searching for a job as well, I came across a website called http://www.millionairevirtualstaffing.com/index.html,
where you are a "virtual assistant." I spoke to one of the owners today and you really are being an assistant but working out of your home.
I know all of the job websites and I am sure in your local paper, there are tons of listings for all types of office jobs, be it an executive assistant or an office manager (I don't know what you your experience is in but I am going by the fact that you listed computers above).
You can inquire from your friends or family if the companies they work for are hiring.
I personally have been looking into all of these websites that say "make money from your home." I hate to say this but so many of them seem like scams, but I have heard of so many people who do this and they really are making a lot of money.
Here's one website I have come across http://www.top-10-online-jobs.com/,
it doesn't hurt to check these types of websites out.
How about becoming a Real Estate agent (which I am currently looking into actually). Taking the test to get your license is very easy. The one major downside (which is not in your or my favor) is that the first several months to a year you will not be making much money. But I hear and know many people who are agents and they make over 6 figures.
Do you still communicate from anyone from your job that could have any leads for you?
Let me know what happens and if you are interested in Mary Kay let me know.
Good luck and hang in there, I am trying to, and believe me I know it's hard.